The Story of Prescion takes places on a world not too different from Earth, only somewhat in the future. Many smaller nations have banned together or been annexed by growing empires of ideology, and now the larger nations vie for control. The largest and most powerful of these nations are Runaria, and Agregorn. It is in Runaria, that the story begins, centered around a main character of the player's choosing, and a handful of other agents within the elite Runarian Special Forces.